Phase I and Pharmacologic Study of Oral ZD9331, A Novel Nonpolyglutamated Thymidylate Synthase Inhibitor, in Adult Patients With Solid Tumors ABSTRACT: Aberrant gene expression is critical for tumor ...

The mutation status of the epidermal growth factor receptor (EGFR) as a selection criterion for therapy with EGFR tyrosine kinase inhibitors (TKI’s) in non-small cell lung cancer (NSCLC) No ...

Accurate classification of tissue samples is an essential tool in disease diagnosis and treatment. The DNA microarray technology enables disease classification based only on gene expression analysis, ...

Microarray technology has been applied to a variety of different fields to address fundamental research questions. The use of microarrays, or DNA chips, to study the gene expression profiles of ...

Wound repair is a complex biological process involving cell migration, proliferation and differentiation of multiple cell types. A number of growth factors, receptors, matrix molecules and proteases ...

The late 1980s were heady days for molecular biologists. PCR was only a few years old. The automated DNA sequencer had just been invented. The Human Genome Project was being debated in Congress.

Reported Data Supports the Potential Extension of HD-MAP Vaccine Delivery to Oncology Indications Recently published data generated by researchers at The University of Queensland and Vaxxas shows ...

From synthetic biology and gene therapy to data storage and biofuel production, the demand for synthetic DNA is rising. (1) Chemicals remove the 5’-hydroxyl protecting group. The nucleosides are rich ...