This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate ...

The field of cancer immunology has witnessed dramatic progress with the advent of immunotherapies targeting the tumor immune microenvironment (TIME).

Scientists have uncovered how a vitamin A metabolite can suppress anti-cancer immunity. Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have uncovered new ...

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain—and offers insights on developing drugs to treat this condition.

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Using newly generated 'optogenetic' tobacco plants, research teams have investigated how plants process external signals. When it comes to survival, plants have a huge disadvantage compared to many ...