While a postdoctoral student at MIT, Tomomi Kiyomitsu discovered how dynein has a role as a motor protein in aligning the chromosomes in the middle of the cell during the metaphase of …

1 Introduction Dynein is a molecular motor that uses the chemical energy of ATP to produce mechanical work on microtubules. Initially discovered as the driving force of flagellar motility in …

In this review, we begin by discussing the assembly, motility, and regulation of the dynein-1 transport machinery, which also serves as a primer for other dynein motors. We then focus on …

Sep 25, 2013 · Dynein is one of the three families of cytoskeletal motor protein. Originally identified 50 years ago as an ATPase in Tetrahymena pyriformis cilia3, dynein was named by …

Dynein binds to four ATP molecules, but only one is involved in the power stroke, shown here at the top in white. The other three sites (shown in gray) are thought to play a regulatory role.

Oct 24, 2025 · Dynein is a minus-end-directed microtubule motor protein, which transports a variety of intracellular cargo by hydrolysing ATP to power its movement along microtubule tracks.

Jul 27, 2025 · Dynein is a family of motor proteins operating within cells. These molecular machines convert chemical energy into mechanical work, enabling various forms of movement …

The protein responsible for movement of cilia and flagella was first discovered and named dynein in 1963 (Karp, 2005). 20 years later, cytoplasmic dynein, which had been suspected to exist …

Dynein is a motor protein which walks along the microtubule toward its minus end, i.e. it is a minus-end directed motor. Dyneins are classified as cytoplasmic (DYNC) or axonemal.

Dynein is a microtubule-based molecular motor that is involved in various biological functions, such as axonal transport, mitosis, and cilia/flagella movement. Although dynein was …